This course is the first of a two-course sequence that emphasizes the physiology and pathophysiology of the cardiovascular, endocrine, gastrointestinal, hematologic, hepatobiliary, immune, integumentary, lymphatic, pulmonary, renal, and urogenital body systems; as well as infectious, neoplastic and transplant disease processes. Students are presented with approaches to basic medical assessments (e.g. diagnostic testing and laboratory values), management approaches that consider activity and exercise guidelines, and common medical interventions for conditions related to physical therapy practice. Clinical cases are discussed by students to reinforce the relevance to physical therapy practice.