This course is designed to develop and strengthen problem-solving skills essential to effective medical decision-making. Students will engage in an in-depth study of diseases/disorders using a body systems approach. Medical knowledge includes epidemiology, etiology, pathophysiology, clinical manifestations, diagnosis, management, and patient education for conditions commonly encountered in primary care. Instruction includes the provision of care in preventive, emergent, acute, chronic, adolescent, and adult populations as it applies to disease processes. The course content supports program learning outcomes by fostering patient-centered knowledge for practice, integrating clinical reasoning and evidence-based decision-making to promote safe, effective, and compassionate care across diverse patient populations. The skills and knowledge gained will directly support performance in supervised clinical rotations and long-term competence in primary care and other medical settings.