This course introduces general research principles and evidence-based practice. This course is designed to present critical analysis of literature pertaining to the intervention components of the Patient/Client Management Model and use the findings to effect clinical care. Common research methods and designs are discussed and applied to clinical problems with integration of patient values as influenced by culture, ethnicity, lifestyles, gender and age into patient-centered clinical decision-making consideration. Basic statistics will be introduced, practiced and appraised in current literature and applied to clinical decision making. This course provides a framework for assignments in subsequent courses in which evidence-based foundations of physical therapy are presented.